IWR-1-endo ≥98%
Supplier: ADIPOGEN CORP MS
AG-CR1-3581-M005
AG-CR1-3581-M025
102988-638EA
124.62
USD
102988-638
102988-640
IWR-1-endo ≥98%
IWR-1-endo
Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of beta-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3beta. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3beta. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay).
Formula:
C₂₅H₁₉N₃O₃ Storage Temperature: Freezer |
MDL Number:
MFCD18086875 CAS Number: 1127442-82-3 |
Specification Test Results
Purity |
|
Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO or DMF. |
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