IWR-1-endo ≥98%

Supplier: ADIPOGEN CORP MS

AG-CR1-3581-M005 AG-CR1-3581-M025
102988-638EA 124.62 USD
102988-638 102988-640
IWR-1-endo ≥98%
IWR-1-endo

Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of beta-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3beta. Stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or GSK-3beta. Tankyrase-1 (TNKS1/PARP5a) and Tankyrase-2 (TNKS2/PARP5b) inhibitor (in vitro auto-PARsylation assay).

Formula: C₂₅H₁₉N₃O₃
Storage Temperature: Freezer
MDL Number: MFCD18086875
CAS Number: 1127442-82-3

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Specification Test Results

Purity 98%
Appearance/Color White to off-white solid.
Solubility Soluble in DMSO or DMF.


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