AdipoRon ≥98% (by NMR)

Supplier: ADIPOGEN CORP MS

Synonyms: SC-396658, 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide, 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide

AG-CR1-0154-M010 AG-CR1-0154-M050
102988-544EA 76.15 USD
102988-544 102988-546
AdipoRon ≥98% (by NMR)
AdipoRon

Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice.

Formula: C₂₇H₂₈N₂O₃
MW: 428.52 g/mol
Storage Temperature: Freezer
MDL Number: MFCD08271060
CAS Number: 924416-43-3

Order Now

Specification Test Results

Purity >98% (NMR)
Appearance/Color White solid.
Solubility Soluble in DMSO, 100% ethanol or methanol. Insoluble in water.

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR