Ganglioside GD3 disodium salt ≥98% (by TLC)

Supplier: ADIPOGEN CORP MS

Synonyms: GD3 . 2Na

AG-CN2-9005-C500 AG-CN2-9005-M001
102988-416EA 263.08 USD
102988-416 102988-418
Ganglioside GD3 disodium salt ≥98% (by TLC)
Ganglioside GD3 disodium salt

Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GD3 induces mitochondrial permeability transition (MPT) without requiring elevated Ca2+ levels and thus triggers Fas-mediated apoptosis. It modulates the activity of Src-family tyrosine kinase Lyn and cell apoptosis. It is involved in several tumor processes and is high abundant in proliferating cells and in the first stage of neuronal differentiation.

Formula: C₇₀H₁₂₃N₃O₂₉·2Na
MW: 1516.8 g/mol
Storage Temperature: Freezer
CAS Number: 62010-37-1

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Specification Test Results

Source/Host Isolated from bovine brain.
Purity 98% (TLC)
Solubility Soluble in water or chloroform:methanol (2:1).
Formulation Lyophilized.

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