Wedelolactone ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one, 7-Methoxy-5,11,12-trihydroxy-coumestan
Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.
Formula:
C₁₆H₁₀O₇ MW: 314.2 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD07778564 CAS Number: 524-12-9 |
Specification Test Results
Source/Host | Isolated from Eclipta prostrata. |
Purity |
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Appearance/Color | Yellow to amber crystalline powder. |
Solubility | Soluble in DMSO or methanol. |
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