Apicidin ≥98% (by HPLC, TLC)
Supplier: ADIPOGEN CORP MS
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Danger
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Synonyms:
cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]
Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells. Promotes either self-renewal or differentiation of embryonic stem cells.
Formula:
C₃₄H₄₉N₅O₆ MW: 623.8 g/mol Storage Temperature: Freezer |
CAS Number:
183506-66-3 UN: 2811 ADR: 6.1,III |
Specification Test Results
Source/Host | Isolated from fungus Fusarium sp. |
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in ethanol or DMSO. |
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