Apicidin ≥98% (by HPLC, TLC)

Supplier: ADIPOGEN CORP MS
Danger

Synonyms: cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl]

AG-CN2-0087-M001 AG-CN2-0087-M005
102987-298EA 83.08 USD
102987-298 102987-300
Apicidin ≥98% (by HPLC, TLC)
Apicidin

Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional activity in human and mouse tumor cell lines. Autophagy inducer in oral squamous cell carcinoma (OSCC) cells. Promotes either self-renewal or differentiation of embryonic stem cells.

Formula: C₃₄H₄₉N₅O₆
MW: 623.8 g/mol
Storage Temperature: Freezer
CAS Number: 183506-66-3
UN: 2811
ADR: 6.1,III

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Specification Test Results

Source/Host Isolated from fungus Fusarium sp.
Purity 98% (HPLC, TLC)
Appearance/Color White to off-white solid.
Solubility Soluble in ethanol or DMSO.

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