N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95%

Supplier: ADIPOGEN CORP MS
Danger

Synonyms: Erlotinib Hydrochloride

SYN-1039-M001 SYN-1039-M005 SYN-1039-M010 SYN-1039-M050
102991-550EA 74.77 USD
102991-550 102991-552 102991-554 102991-556
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride ≥95%
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is 1000-fold more sensitive for EGFR than for c-Src or v-Abl.

Formula: C22H24ClN3O4
MW: 429.901 g/mol
Storage Temperature: Freezer
MDL Number: MFCD07781272
CAS Number: 183319-69-9

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO. Slightly soluble (1mg/ml) in ethanol.

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