BI-D1870

Supplier: ADIPOGEN CORP MS

Synonyms: 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one

SYN-1020-M001 SYN-1020-M005 SYN-1020-M010 SYN-1020-M050
102991-400EA 134.31 USD
102991-400 102991-402 102991-404 102991-406
BI-D1870
BI-D1870

BI-D1870 is a small molecule, specific inhibitor of p90 RSK (ribosomal S6 kinase) isoforms RSK1, RSK2, RSK3 and RSK4, both in vitro and in vivo, with IC(50)s are 31nM, 24nM, 18nM, 15nM, respectively. It shows a 10- to 100-fold selectivity for RSK over MST2, GSK-3beta, MARK3, CK1 and Aurora B.

Formula: C₁₉H₂₃F₂N₅O₂
MW: 391.423 g/mol
MDL Number: MFCD11223662
CAS Number: 501437-28-1

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