(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid

Supplier: ADIPOGEN CORP MS

Synonyms: Naproxen, (S)-2-(6-Methoxynaphthalen-2-yl)propanoic acid, (S)-(+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid

CDX-N0061-G001 CDX-N0061-G010

102990-630EA 42.92 USD

102990-630 102990-632

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid

(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid

Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II).

Formula: C₁₄H₁₄O₃
MW: 230.26 g/mol

MDL Number: MFCD00010500
CAS Number: 22204-53-1

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