4-Hydroxyphenylpyruvic Acid

Supplier: ADIPOGEN CORP MS

Synonyms: 3-(4-Hydroxyphenyl)-2-oxopropanoic acid

CDX-H0013-G001 CDX-H0013-G005
102990-214EA 70.62 USD
102990-214 102990-216
4-Hydroxyphenylpyruvic Acid
4-Hydroxyphenylpyruvic acid

Keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydrogenase and is formed during tyrosine metabolism. The conversion from tyrosine to 4-HPPA is catalyzed by tyrosine aminotransferase. 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment. A deficiency in the catalytic activity of HPD is known to lead to tyrosinemia type III, an autosomal recessive disorder characterized by elevated levels of blood tyrosine and massive excretion of tyrosine derivatives into urine.

Formula: C₉H₈O₄
MW: 180.16 g/mol
MDL Number: MFCD00002591
CAS Number: 156-39-8

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