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Berberine chloride

Supplier: ADIPOGEN CORP MS

CDX-B0212-G010 CDX-B0212-G025 CDX-B0212-G050

102989-404EA 78.92 USD

102989-404 102989-406 102989-408

Berberine chloride

Berberine chloride

Natural fluorescent dye, used in histology for staining heparin in mast cells. An isoquinoline alkaloid, which shows antibacterial, antifungal, anti-inflammatory, anti-oxidant, antidiabetic, antiviral and anticancer activity. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. Broad spectrum enzyme inhibitor, affects N-acetyltransferase, cyclooxygenase-2, and topoisomerase activities and gene/protein expression. Increases adiponectin expression, upregulates LDLR and insulin receptor. Anti-hyperglycemic, by inhibition of aldose reductase, inducing glycolysis, preventing insulin resistance through increasing insulin receptor expression and acting like incretins. Activates AMPK and ERK. Potent, uncompetitive, reversible IDO 1 inhibitor with IC50 values of 7 µM (cell-based assay) and 9.3 µM (enzymatic assay), and Ki value 8µM.

Formula: C₂₀H₁₈ClNO₄

MDL Number: MFCD00011939
CAS Number: 633-65-8

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