2-Bromo-1-ethylpyridinium tetrafluoroborate
Supplier: ADIPOGEN CORP MS
Synonyms:
2-Bromo-1-ethyl-pyridinium tetrafluoroborate, 2-Bromo-1-ethylpyridin-1-ium tetrafluoroborate
Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or Calpha,Calpha-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.
Formula:
C₇H₉BBrF₄N MW: 273.86 g/mol |
MDL Number:
MFCD00060046 CAS Number: 878-23-9 |
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