AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride)

Supplier: ADIPOGEN CORP MS

Synonyms: 4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride, AEBSF hydrochloride

AG-CR1-3610-M050 AG-CR1-3610-M250 AG-CR1-3610-G001

102988-754EA 55.38 USD

102988-754 102988-756 102988-758

AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride)

AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulphonylfluoride hydrochloride)

Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP kinases. beta-Secretase inhibitor. Shown to inhibit beta-amyloid peptide production and enhance APP (amyloid precursor protein) secretion in several cell lines at millimolar concentrations.

Formula: C₈H₁₁ClFNO₂S
MW: 239.69 g/mol

MDL Number: MFCD00132962
CAS Number: 30827-99-7
UN: 3261
ADR: 8,II

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