AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride)
Supplier: ADIPOGEN CORP MS
Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF. Potent, selective inhibitor of Site-1-protease (S1P). Used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation by selectively inhibiting S1P. NAD(P)H oxidase inhibitor. Inhibits activation of TGFbeta and activates JNK and p38 MAP kinases. beta-Secretase inhibitor. Shown to inhibit beta-amyloid peptide production and enhance APP (amyloid precursor protein) secretion in several cell lines at millimolar concentrations.
Formula:
C₈H₁₁ClFNO₂S |
MDL Number:
MFCD00132962 CAS Number: 30827-99-7 UN: 3261 ADR: 8,II |
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