Loxoribine

Supplier: ADIPOGEN CORP MS

AG-CR1-3584-M005 AG-CR1-3584-M025
102988-650EA 41.54 USD
102988-650 102988-652
Loxoribine

Guanosine analog derivatized at position N7 and C8. Very potent immunostimulatory compound that increases cytokine production. Antitumor and antiviral activity compound. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7). Co-incubation with thymidine homopolymer oligodeoxynucleotides (ODN) redirected the stimulatory effect of loxoribine away from TLR7 toward TLR8. Induces autophagy and autophagy-induced cell death in Caco-2 cells. Shows adjuvant activity to increase the effectiveness of vaccines.

Formula: C₁₃H₁₇N₅O₆
MDL Number: MFCD00867591
CAS Number: 121288-39-9

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