2-Carboxyphenyl Salicylate ≥98%

Supplier: ADIPOGEN CORP MS
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Synonyms: 2-Salicyloyloxybenzoic Acid, O-Salicyloylsalicylic Acid, Salicylic Acid 2-Carboxyphenyl Ester, Salsalate

AG-CR1-3574-G001 AG-CR1-3574-G005
102988-604EA 34.62 USD
102988-604 102988-606
2-Carboxyphenyl Salicylate ≥98%
2-Carboxyphenyl salicylate

Nonacetylated salicylate. Non-steroidal anti-inflammatory drug (NSAID). Reduces pain and inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis and related rheumatic conditions. Prostaglandin synthesis inhibitor in vivo. Inactivates cyclooxygenase-1 (COX-1) and -2 (COX-2). IKKbeta/NF-kappaB inhibitor (at significantly higher concentrations than required for COX inhibition). Used to target inflammation in the treatment of insulin resistance, type 2 diabetes, or rheumatic pain. It reduces blood glucose concentrations in patients with type 2 diabetes, as well as in insulin-resistant patients without diabetes. Reduces blood glucose, triglyceride, free fatty acid and C-reactive protein concentrations, improves glucose utilization and increases circulating insulin and adiponectin concentrations in obese adults at risk for the development of type 2 diabetes as well as for patients with type 2 diabetes. Dimeric prodrug comprising two esterified salicylate moieties. It is advantageous over sodium salicylate because it is insoluble at the acid pH of the stomach and passes suspended but undissolved into the small intestine, sparing the gastric mucosa direct contact.

Formula: C₁₄H₁₀O₅
MW: 258.23 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00020252
CAS Number: 552-94-3
UN: 3077
ADR: 9,

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Specification Test Results

Purity 98%
Appearance/Color White to off-white powder.
Solubility Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water.

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