Triptolide
Supplier: ADIPOGEN CORP MS
Potent immunosuppressant with anti-inflammatory and antitumor properties. Exhibits potent antiproliferative activity, induces apoptosis, modulates autophagy and inhibits cell cycle regulators. Inhibits global gene transcription by inducing degradation of RNA polymerase II (Pol II) and by inhibiting the ATPase activity of XPB (a subunit of the general transcription factor TFIIH). Human dCTP pyrophosphatase 1 inhibitor. Interferes with a number of transcription factors including p53, NF-kappaB, nuclear factor of activated T cells (NFAT) and heat shock factor protein 1 (HSF-1). Shown to inhibit aromatase activity. Shows antifertility activity and antipolycystic kidney disease effects.
Formula:
C₂₀H₂₄O₆ MW: 360.41 g/mol |
MDL Number:
MFCD00210565 CAS Number: 38748-32-2 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...