Genistein

Supplier: ADIPOGEN CORP MS

Synonyms: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one, 4',6'-Dihydroxy-3-(4-hydroxyphenyl)benzo(e)oxacyclohex-2-en-4-on, 5,7-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one, 4',5,7-Trihydroxyisoflavone

AG-CN2-0427-M010 AG-CN2-0427-M050 AG-CN2-0427-M250
102988-242EA 34.62 USD
102988-242 102988-244 102988-246
Genistein
Genistein

Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Inhibitor of mammalian DNA topoisomerase II. Anticancer agent, inducing cell cycle arrest and apoptosis. Antiangiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. Binds estrogen receptor beta. Can increase the rate of growth of some ER expressing breast cancers. Potent alpha-glucosidase inhibitor. Anthelmintic. Anti-diabetic. Activates nuclear receptors, oestrogen receptors and peroxisome proliferator-activated receptors (all PPAR isoforms) and it inhibits various enzyme activities. Inhibitor of GLUT4-mediated glucose uptake in 3T3-L1 adipocytes. Stimulator of autophagy vacuolization. Antioxidant. TRAIL sensitizer. Acts as an agonist at the GPR30 receptor. MALT1 inhibitor DNA methyltransferase inhibitor. Genistein exhibits synergistic antibacterial effects on MRSA.

Formula: C₁₅H₁₀O₅
MW: 270.24 g/mol
MDL Number: MFCD00016952
CAS Number: 446-72-0

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