D-(-)-N-Methylglucamine ≥95% (by NMR)
Supplier: ADIPOGEN CORP MS
Synonyms:
Meglumine, (-)-1-Deoxy-1-(methylamino)-D-glucitol, N-Methyl-D-glucamine, (-)-N-Methyl-D-glucamine, (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol, (-)-1-Methylamino-1-deoxy-D-glucitol
Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances. Counter ion used to replace sodium. It is impermeable towards cell membranes with comparable osmotic activity like sodium. Widely used in the preparation of contrast/radiopaque media in combination with iodine containing compounds, such as diatrizoate meglumine and iodipamide meglumine. Examples of meglumine-combined drugs are flunixin meglumine (used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis).
Formula:
H₃CNHCH₂(CH(OH))₄CH₂OH MW: 195.22 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00004707 CAS Number: 6284-40-8 |
Specification Test Results
Source/Host | Synthetic. Amino sugar derived from sorbitol. |
Purity |
|
Appearance/Color | White to off-white crystalline powder. |
Solubility | Soluble in DMSO or water. Slightly soluble in ethanol. |
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