Aphidicolin (from Phoma sp. BS 7210) ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS

Synonyms: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-Bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol

BVT-0307-M001 BVT-0307-M005 BVT-0307-M025

102513-744EA 90 USD

102513-744 102513-746 102513-748

Aphidicolin (from Phoma sp. BS 7210) ≥98% (by HPLC)

Aphidicolin

(+)-Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication.

Useful for cell synchronization
Antibiotic
Antileishmanial agent

Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.

White to off-white solid

After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at +4°C.

Soluble in DMSO (50 mg/ml), methanol (10 mg/ml) or 100% ethanol; insoluble in water.

Formula: C₂₀H₃₄O₄
MW: 338.488 g/mol
Storage Temperature: Refrigerator

MDL Number: MFCD00083214
CAS Number: 38966-21-1

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