Geldanamycin (from Streptomyces hygroscopicus) ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS

Synonyms: (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-Hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

BVT-0196-M005 BVT-0196-C100 BVT-0196-C500 BVT-0196-M001

102513-596EA 76.15 USD

102513-596 102513-598 102513-592 102513-594

Geldanamycin (from Streptomyces hygroscopicus) ≥98% (by HPLC)

Geldanamycin

Geldanamycin is a potent nuclear hormone receptor family inhibitor.

Antibiotic
Inhibits c-mycgene expression in murine lymphoblastoma cells
Potent antitumor compound

Antibiotic. pp60src tyrosine kinase inhibitor. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products.

Solid

After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at -20°C.

Colour: Yellow

Formula: C₂₉H₄₀N₂O₉
MW: 560.64 g/mol
Storage Temperature: Freezer

MDL Number: MFCD00274570
CAS Number: 30562-34-6

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