Orlistat ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS

Synonyms: N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester, (S)-(S)-1-((2S,3S)-3-Hexyl-4-oxooxetan-2-yl)tridecan-2-yl 2-formamido-4-methylpentanoate

AG-CN2-0050-M050 AG-CN2-0050-M250
102515-856EA 34.62 USD
102515-856 102515-858
Orlistat ≥98% (by HPLC)
Orlistat

Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways.

Formula: C₂₉H₅₃NO₅
MW: 495.75 g/mol
Storage Temperature: Freezer
MDL Number: MFCD05662360
CAS Number: 96829-58-2

Order Now

Specification Test Results

Source/Host Synthetic. Originally isolated from Streptomyces sp.
Purity 98% (HPLC)
Appearance/Color White to off-white solid.
Solubility Soluble in DMSO, ethanol or DMF.

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR