Orlistat ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
Synonyms:
N-Formyl-L-leucine (1S)-1-[[(2S,3S)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl Ester, (S)-(S)-1-((2S,3S)-3-Hexyl-4-oxooxetan-2-yl)tridecan-2-yl 2-formamido-4-methylpentanoate
Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways.
Formula:
C₂₉H₅₃NO₅ MW: 495.75 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD05662360 CAS Number: 96829-58-2 |
Specification Test Results
Source/Host | Synthetic. Originally isolated from Streptomyces sp. |
Purity |
|
Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO, ethanol or DMF. |
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