Streptozocin ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
Synonyms:
1-Methyl-1-nitroso-3-((2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)urea, Streptozotocin
Potent alkylating agent and potent DNA methylating agent.
- Diabetes inducer
- Nitric oxide donor
- Anti-cancer agent used in chemotherapy
Antibiotic. Diabetogenic. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells. Mutagenic. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter. O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (O-GlcNAcase) inhibitor. Genotoxic. Induces DNA damage. Produces DNA strand breaks. Cell death inducer. Antineoplastic. Anti-cancer agent used in chemotherapy. Induces cell cylce arrest at G2.
Off-white to pale yellow powder
Stable for at least two years after receipt when stored at -20°C.
Soluble in water or ethanol
Formula:
C₈H₁₅N₃O₇ MW: 265.2 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00006607 CAS Number: 18883-66-4 |
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