[4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic Acid ≥98%
Supplier: ADIPOGEN CORP MS
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Danger
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Synonyms:
2-((4-Chloro-6-((2,3-dimethylphenyl)amino)pyrimidin-2-yl)thio)acetic acid, WY-14643, Pirinixic acid
Potent peroxisome proliferator-activated receptor (PPARalpha) activator. Activates also PPARgamma but not PPARdelta. Potent anti-hypercholesterolemic agent. Hypolipidemic compound. Lipogenesis inducer. Tumor promoter. Causes increased cell proliferation and decreased apoptosis. Anti-inflammatory. Inhibits NF-kappaB transcriptional activity and decreases the inflammatory response by reducing the production of inflammatory cytokines (TNF-alpha, IL1beta). Reduces oxidative stress. Increases fatty acid oxidation. Directly affects insulin signaling. Increases glucose uptake. Reviews.
Formula:
C₁₄H₁₄ClN₃O₂S MW: 323.80 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00191335 CAS Number: 50892-23-4 |
Specification Test Results
Purity |
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Appearance/Color | Off-white solid. |
Solubility | Soluble in ethanol, DMSO, dimethyl formamide or PBS (pH 7.2). |
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