Cyclopamine ≥98%

Supplier: ADIPOGEN CORP MS
Warning

Synonyms: (2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol

AG-CN2-0028-M001 AG-CN2-0028-M005
102515-772EA 34.62 USD
102515-772 102515-774
Cyclopamine ≥98%
Cyclopamine

Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer.

Formula: C₂₇H₄₁NO₂
MW: 411.63 g/mol
Storage Temperature: Freezer
MDL Number: MFCD09878269
CAS Number: 4449-51-8

Order Now

Specification Test Results

Source/Host Isolated from Veratrum californicum.
Purity 98%
Appearance/Color White to off-white solid.
Solubility Soluble in ethanol, methanol, DMF or DMSO. Insoluble in water.

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR