Y-27632 dihydrochloride ≥98% (by HPLC)
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
Y-27632 2HCl, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide dihydrochloride, Rock inhibitor y-27632, trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks generation of inflammatory cytokines. Stem cell research modulator. Prevents apoptosis and enhances the survival and cloning efficiency of dissociated human embryonic stem (hES) cells without affecting their pluripotency. Increases survival rate of hES cells undergoing cryopreservation.
Formula:
C₁₄H₂₁N₃O·2HCl MW: 320.26 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD03490488 CAS Number: 129830-38-2 | 146986-50-7 (free base) |
Specification Test Results
Purity | >98% (HPLC)Contains approx. 1.4% water. |
Appearance/Color | White to pale yellow solid. |
Solubility | Soluble in water, DMSO (25mg/ml) or methanol (25mg/ml). |
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