Y-27632 dihydrochloride ≥98% (by HPLC)

Supplier: ADIPOGEN CORP MS
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Synonyms: Y-27632 2HCl, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide dihydrochloride, Rock inhibitor y-27632, trans-4-((R)-1-Aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride

AG-CR1-3564-M001 AG-CR1-3564-M005 AG-CR1-3564-M025
102516-288EA 62.31 USD
102516-288 102516-290 102516-292
Y-27632 dihydrochloride ≥98% (by HPLC)
Y-27632 dihydrochloride

Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks generation of inflammatory cytokines. Stem cell research modulator. Prevents apoptosis and enhances the survival and cloning efficiency of dissociated human embryonic stem (hES) cells without affecting their pluripotency. Increases survival rate of hES cells undergoing cryopreservation.

Formula: C₁₄H₂₁N₃O·2HCl
MW: 320.26 g/mol
Storage Temperature: Freezer
MDL Number: MFCD03490488
CAS Number: 129830-38-2 | 146986-50-7 (free base)

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Specification Test Results

Purity >98% (HPLC)Contains approx. 1.4% water.
Appearance/Color White to pale yellow solid.
Solubility Soluble in water, DMSO (25mg/ml) or methanol (25mg/ml).

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