3-Isobutyl-1-methylxanthine
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
2,6-Dihydroxy-3-isobutyl-1-methylpurine, IBMX, 3,7-Dihydro-3-isobutyl-1-methyl-1H-purine-2,6-dione, 3-Isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.
Formula:
C₁₀H₁₄N₄O₂ MW: 222.25 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00005584 CAS Number: 28822-58-4 |
Specification Test Results
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO, ethanol or methanol. Insoluble in water. |
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