Smoothened Agonist ≥98% (by NMR)

Supplier: ADIPOGEN CORP MS

Synonyms: 3-Chloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide, 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(4-pyridinyl)benzyl]-1-benzothiophene-2-carboxamide, SAG

AG-CR1-3506-M001 AG-CR1-3506-M005
102516-230EA 69.23 USD
102516-230 102516-232
Smoothened Agonist ≥98% (by NMR)
Smoothened agonist

Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.

Formula: C₂₈H₂₈ClN₃OS
MW: 490.062 g/mol
Storage Temperature: Freezer
MDL Number: MFCD22581513
CAS Number: 912545-86-9

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Specification Test Results

Purity 98% (NMR)
Appearance/Color Off-white to light yellow powder.
Solubility Soluble in DMSO. Sparingly soluble in water (acidification with HCl increases water solubility).

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