Smoothened Agonist ≥98% (by NMR)
Supplier: ADIPOGEN CORP MS
Synonyms:
3-Chloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-(pyridin-4-yl)benzyl)benzo[b]thiophene-2-carboxamide, 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[3-(4-pyridinyl)benzyl]-1-benzothiophene-2-carboxamide, SAG
AG-CR1-3506-M001
AG-CR1-3506-M005
102516-230EA
69.23
USD
102516-230
102516-232
Smoothened Agonist ≥98% (by NMR)
Smoothened agonist
Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations. Potent activator of VEGF expression in vitro.
Formula:
C₂₈H₂₈ClN₃OS MW: 490.062 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD22581513 CAS Number: 912545-86-9 |
Specification Test Results
Purity |
|
Appearance/Color | Off-white to light yellow powder. |
Solubility | Soluble in DMSO. Sparingly soluble in water (acidification with HCl increases water solubility). |
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