Bisindolylmaleimide I·hydrochloride ≥98% (by NMR)
Supplier: ADIPOGEN CORP MS
AG-CR1-0110-M001
AG-CR1-0110-M005
102516-154EA
76.15
USD
102516-154
102516-156
Bisindolylmaleimide I·hydrochloride ≥98% (by NMR)
Bisindolylmaleimide I hydrochloride
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
Formula:
C₂₅H₂₄N₄O₂·HCl MW: 452.5·36.5 g/mol Storage Temperature: Freezer |
CAS Number:
176504-36-2 |
Specification Test Results
Purity |
|
Appearance/Color | Orange to red powder. |
Solubility | Soluble in DMSO or methanol. Slightly soluble in water. |
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