PD 184,352 ≥95% (by HPLC, total nitrogen)
Supplier: ADIPOGEN CORP MS
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Warning
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Synonyms:
2-(2-Chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide, 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide, PD 184352, CI-1040
AG-CR1-0029-M001
AG-CR1-0029-M005
102515-984EA
27.69
USD
102515-984
102515-986
PD 184,352 ≥95% (by HPLC, total nitrogen)
PD 184,352
MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.
Formula:
C₁₇H₁₄ClF₂IN₂O₂ MW: 478.7 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD02683961 CAS Number: 212631-79-3 |
Specification Test Results
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in DMSO. |
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