Bisindolylmaleimide I ≥98% (by NMR)
Supplier: ADIPOGEN CORP MS
Synonyms:
3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, GF 109203X
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competetive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
Formula:
C₂₅H₂₄N₄O₂ MW: 412.48 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00236428 CAS Number: 133052-90-1 |
Specification Test Results
Purity |
|
Appearance/Color | Orange solid. |
Solubility | Soluble in DMSO. |
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