Bisindolylmaleimide I ≥98% (by NMR)

Supplier: ADIPOGEN CORP MS

Synonyms: 3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione, GF 109203X

AG-CR1-0009-M001 AG-CR1-0009-M005
102515-898EA 76.15 USD
102515-898 102515-900
Bisindolylmaleimide I ≥98% (by NMR)
Bisindolylmaleimide I

Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competetive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.

Formula: C₂₅H₂₄N₄O₂
MW: 412.48 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00236428
CAS Number: 133052-90-1

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Specification Test Results

Purity 98% (NMR)
Appearance/Color Orange solid.
Solubility Soluble in DMSO.

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