Nigericin sodium salt ≥98% (by TLC)

Supplier: ADIPOGEN CORP MS

Synonyms: Sodium (R)-2-((2R,3S,6R)-6-(((2S,4R,5R,7R,9R,10R)-2-((2S,2'R,3'S,5R,5'R)-5'-((2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl)-2,3'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)methyl)-3-methyltetrahydro-2H-pyran-2-yl)propanoate

AG-CN2-0020-M005 AG-CN2-0020-M025
102515-730EA 76.15 USD
102515-730 102515-732
Nigericin sodium salt ≥98% (by TLC)
Nigericin sodium salt

Nigericin is a high-affinity ionophore for monovalent cations such as H+, K+, Na+, Pb2+.


  • Disrupts mebrane potential of mitochondria
  • Autophagy modulator
  • High-affinity ionophore


Antibiotic. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential of mitochondria. NLRP3/NALP3 activator. Signals through pannexin-1 to induce caspase-1 maturation and IL-1beta processing and release. Autophagy modulator.


White to off-white powder


Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.


Soluble in methanol, ethanol, dichlormethane or ethyl acetate. Insoluble in water.

Formula: C₄₀H₆₇NaO₁₁
MW: 746.94 g/mol
Storage Temperature: Freezer
MDL Number: MFCD00036825
CAS Number: 28643-80-3

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