Anti-CD40 Rat Monoclonal Antibody [clone: FGK45]

Supplier: Adipogen

AG-20B-0036-C100 AG-20B-0036-C500

102514-338EA 207.69 USD

102514-338 102514-340

Anti-CD40 Rat Monoclonal Antibody [clone: FGK45]

Antibodies

CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.

Stable for at least 1 year after receipt when stored at -20°C.

Purified from concentrated hybridoma tissue culture supernatant.

Purity: >95% (SDS-PAGE)

Type:
Antigen: CD40
Clonality: Monoclonal
Clone: FGK45
Conjugation:
Epitope:
Host: Rat
Isotype: IgG2a
Reactivity: Mouse

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