Phorbol-12-myristate-13-acetate ≥99% (by TLC)
Supplier: Enzo Life Sciences
Synonyms:
TPA, Phorbol 12-myristate 13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate
PKC activator
PKC activator (10-100 ng/ml). Most commonly used phorbol ester. Causes an extremely wide range of effects in cells and tissues. Very potent mouse skin tumor promoter. Inhibits apoptosis induced by Fas, but induces apoptosis in HL-60 promyelocytic leukemia cells.
Formula:
C₃₆H₅₆O₈ MW: 616.836 g/mol |
MDL Number:
MFCD00036736 CAS Number: 16561-29-8 |
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