Phorbol-12-myristate-13-acetate 95%

Supplier: Thermo Scientific Chemicals
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Synonyms: TPA, Phorbol 12-myristate 13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate

J63916-LB0 J63916-MCR
AAJ63916-LB0EA 318.11 USD
AAJ63916-LB0 AAJ63916-MCR
Phorbol-12-myristate-13-acetate 95%
Phorbol-12-myristate-13-acetate

Activates protein kinase C and promotes skin tumors in mice.


PMA activates Ca2+ - ATPase and potentiates forskolin-induced cAMP formation. Used to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.


Activates protein kinase C and promotes skin tumors in mice.


Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.


Precaución: Light sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Formula: C₃₆H₅₆O₈
MW: 616.836 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00036736
CAS Number: 16561-29-8
Merck Index: 14,7332

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Specification Test Results

Appearance (Color) White to pale cream
Form Powder, film or foam, solid
Assay from Suppliers CofA ≥94.0%

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