You Searched For: Puromycin dihydrochloride


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Supplier: Enzo Life Sciences
Description: Inhibits protein synthesis
Supplier: MP Biomedicals
Description: Puromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis and 4) antitrypanosome activity.
Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from Streptomyces alboniger. It is a broad spectrum antibiotic with antitumor activity, as an inhibitor of protein synthesis and has been used to study transcription regulatory mechanisms that control the sequential and coordinate expression of genes during cell differentiation.

Catalog Number: (62111-170)
Supplier: Corning
Description: Puromycin dihydrochloride is a nucleoside antibiotic and protein synthesis inhibitor.

Supplier: MP Biomedicals
Description: Puromycin dihydrochloride is a part of the amino-nucleoside family of antibiotics and is derived from <i>Streptomyces alboniger</i>.

SDS

Catalog Number: (10766-886)
Supplier: Mirus Bio
Description: Puromycin antibiotic ensures effective positive selection of cells expressing the puromycin-N-acetyltransferase (<i>pac</i>) gene.

SDS


Supplier: Ambeed
Description: Puromycin dihydrochloride ≥98%

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Supplier: Thermo Scientific Chemicals
Description: Causes premature chain termination in protein synthesis
Supplier: Adipogen
Description: Aminonucleoside antibiotic. Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems. Inhibits the transport of proteins into the mitochondria in vitro. Reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Apoptosis inducer. Inhibits the growth of Gram-positive bacteria, various animal and insect cells. Fungi and Gram-negative bacteria are resistant due to the low permeability to the antibiotic. Antineoplastic agent. Used in cell biology as selective agent in cell culture systems. It allows selection for cells that contain the resistance gene puromycin N-acetyl-transferase (PAC). Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/ml. Puromycin-resistant stable mammalian cell lines can be generated in less than one week.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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