You Searched For: Docusate sodium

Catalog Number: (I-1345.0050BA)

Supplier: Bachem Americas

Description: See also I-1350 and K-1490.

Catalog Number: (103009-034)

Supplier: Anaspec Inc

Description: This peptide is histone H3 (44-63) with acetylation at Lys56. Lys56 acetylation occurs during premeiotic and mitotic S phases and persists through DNA damage repair and is catalyzed by the Rtt109-Vps75 histone acetyltransferase (HAT) complex. A deficiency of acetylated Lys56 in histone H3 is implicated in spontaneous chromosome breaks during mitosis, suggesting that this modification is important for replisome integrity and DNA replication.
Sequence:GTVALREIRRYQ-K(Ac)-STELLIR
MW:2444.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103007-656)

Supplier: Anaspec Inc

Description: This is a H3 peptide acetylated at the lysine residue at the 14th position. This peptide has been shown to act as part of the active promoter state and the extent of its acetylation could be driven by cis regulatory elements such as CpG contents at promoters. It's expression has been shown to be decreased as malignancy of ovarian epithelial tumors increased, suggesting that this peptide could act as a prognostic marker although it does not show significant relation with the occurence or development of ovarian tumors.
Sequence:KSTGG-K(Ac)-APRKQ
MW:1199.4 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Bachem Americas

Description: The bioactive tetrapeptide goralatide which corresponds to the N-terminus of Thymosin β₄, is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP has been shown to reduce the damage to specific compartments in the bone marrow resulting from treatment with chemotherapeutic agents, ionizing radiations, hyperthermy, or phototherapy. It protects from doxorubicin-induced toxicity. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE).

Catalog Number: (103008-312)

Supplier: Anaspec Inc

Description: This peptide is Histone H3 amino acid residues 1-21. It is acetylated at lysine 18 with a C-terminal GG linker followed by a biotinylated lysine. The acetylation of histone H3 at lysine 18 is used to predict prostrate cancer recurrence and clinical outcome of patients with both lung and kidney cancer. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ARTKQTARKSTGGKAPR-K(Ac)-QLA-GGK(Biotin)-NH2
MW:2764.3 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (100281-122)

Supplier: Indofine Chemical Company

Description: Rare Organics & BioChemicals 6382-93-0 5gm Z-D-Arg-OH 308.3 Room temperature.

Supplier: Bachem Americas

Description: See also I-1160, I-1960, L-1545, M-1130, and M-1140.

Catalog Number: (103008-116)

Supplier: Anaspec Inc

Description: This peptide is Histone H3 amino acid residues 21 to 43. It is acetylated at lysine 27 with a C-terminal G linker followed by a biotinylated lysine. Acetylation of histone H3 at lysine 27 is associated with many active mammalian genes. In Arabidopsis thaliana, the acetylated histone at lysine 27 is nontransposable element gene-specific. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:ATKAAR-K(Ac)-SAPSTGGVKKPHRYRPG-GK(Biotin)-NH2
MW:2974.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: TCI America

Description: CAS Number: 1946-82-3
MDL Number: MFCD00008233
Molecular Formula: C8H16N2O3
Molecular Weight: 188.23
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 254
Specific rotation [a]20/D: 4.0 deg (C=4, H2O)

SDS Certificates

Catalog Number: (103009-158)

Supplier: Anaspec Inc

Description: This peptide is histone H4 (1-25) with acetylation at Lys8. It is biotinylated through a C-terminal GSGSK linker. Acetylation at Lys8 is crucial to the recruitment of the SWI/SNF (switch/sucrose non-fermenting) chromatin-remodeling complex through the bromodomain-containing protein BRG1 for transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:SGRGKGG-K(Ac)-GLGKGGAKRHRKVLRDN-GSGSK(Biotin)
MW:3274.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (10230-028)

Supplier: Bioss

Description: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.

Catalog Number: (10230-112)

Supplier: Bioss

Description: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.

Catalog Number: (103008-518)

Supplier: Anaspec Inc

Description: This peptide is derived from amino acid residues 372-389 of human p53 tumor suppressor protein and is acetylated at Lys382. It is biotinylated at its N-terminus through a 6-carbon LC linker. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo.
Sequence:Biotin-LC-KKGQSTSRHK-K(Ac)-LMFKTEG
MW:2473 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: (103009-070)

Supplier: Anaspec Inc

Description: This peptide is histone H4 (1-25) with acetylation at Lys12 and Lys16. It is biotinylated through a C-terminal GSGSK linker. It has been shown that human histone H4 is preferentially acetylated first at Lys16, then at Lys12. Diacetylated histone H4 has been shown to bind repressor protein TUP1. Acetylation of histone H4 also regulates heterochromatin formation by promoting the binding of bromodomains to p300 and transcription factor TAFII250 and inhibiting interactions with SIR3. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:SGRGKGGKGLG-K(Ac)-GGA-K(Ac)-RHRKVLRDN-GSGSK(Biotin)
MW:3316.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Bachem Americas

Description: The fluorogenic substrate Boc-FSR-AMC is preferentially hydrolyzed by coagulation factor XIa. Boc-FSR-AMC is also highly susceptible to the proteases in yeast mitochondrial matrix as well as to tryptase from rat mast cells. In addition, the substrate is cleaved by acrosin from the ascidian Halocynthia roretzi.

Supplier: Bachem Americas

Description: The FA-peptides M-1400 and M-1410 are common ACE substrates and thus filed in the corresponding product family. For our 3-(2-furyl)acryloyl-amino acids (FA-amino acids) and the labeling reagent FA-OSu (Q-1245), please see the Amino Acids section.