You Searched For: Cytosine-beta-D-arabinofuranoside hydrochloride


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Catalog Number: (TS22718-0010)
Supplier: Thermo Scientific Chemicals
Description: Cytosine-β-D-arabinofuranoside hydrochloride 99%, crystalline


Supplier: MP Biomedicals
Description: Cytosine β-D-arabinofuranoside hydrochloride is an anti-leukemic agent. It results in DNA fragmentation and inhibition of replication. In addition this compound does not have any effects on RNA synthesis. Cytosine β-D-arabinofuranoside hydrochloride can function as a ligand which shows strong affinity and selectivity for the Translocator protein (TSPO). Studies suggest that Cytosine β-D-arabinofuranoside hydrochloride can down-regulate deoxycytidine kinase in acute myeloid leukemia murine cell lines which inhibits the phosphorylation of several deoxyribonucleosides. Furthermore, Cytosine β-D-arabinofuranoside hydrochloride can be inhibited in myeloid leukemic cells via suppression of ENT1 promoter activity, responsible for transporting Cytosine β-D-arabinofuranoside into the cell.

SDS

Supplier: Thermo Scientific Chemicals
Description: Interferes with the synthesis of DNA
Supplier: Ambeed
Description: Cytosine-β-D-arabinofuranoside hydrochloride 97%

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