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Description: Tested for absence of detectable aldehydes and ammeline. DNase-, RNase-, and protease-free.

Catalog Number: MK771687

Supplier: AVANTOR PERFORMANCE MATERIALS US

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Description: Guanidine Hydrochloride is a protein denaturant and thus having an important role in molecular weight determinations.
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase. Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins. It apparently disrupts hydrogen bonds which hold the protein in its unique structure. However, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions.

Catalog Number: IC820539

Supplier: MP Biomedicals

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Description: Guanidine Thiocyanate is used in the isolation of RNA.

Catalog Number: IB05100

Supplier: IBI Scientific

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Description: Storage: Room Temperature
Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds, it is a strong chaotropic agent. Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a free flowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical.
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. Guanidine hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins.

Catalog Number: 76177-762

Supplier: MP Biomedicals

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Description: Sulfamic Acid, Grade: ACS Reagent, Cas number: 5329-14-6, Molecular Formula: NH2SO3H, Molecular weight: 97.09g/mol, Appearance/Form: Colorless/white Solid, Size: 2.50K Poly natural

Catalog Number: RCRDCS110100B1

Supplier: Ricca Chemical

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Description: Guanidine Hydrochloride is an ionic denaturant that rapidly and effectively denatures most proteins

Catalog Number: IB05080

Supplier: IBI Scientific

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Description: CAS: 593-84-0; EC No: 209-812-1; MDL No: MFCD00013027 Crystalline/Powder; Molecular Formula: CH5N3·HSCN; MW: 118.16 Melting Point: 120-122°

Catalog Number: BT143285-100G

Supplier: BeanTown Chemical

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Description: Guanidine Thiocyanate is a chaotropic agent and strong protein denaturant which inactivates nucleases approximately 2.5 times faster than guanidine hydrochloride.

Catalog Number: IC820991

Supplier: MP Biomedicals

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Description: Powder

Catalog Number: AAJ65485-A1

Supplier: Thermo Scientific Chemicals

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Description: Applications
Guanidine hydrochloride can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA. It is a strong chaotropic agent useful for the denaturation and subsequent refolding of protein, it can solubilize insoluble or denatured proteins such as inclusion bodies and be used for the recovery of periplasmic proteins. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Also used in the isolation of RNA.
Product Description
The crystal structure of Guanidine hydrochloride consists of a network of guanidinium cations and chloride anions linked by N–H•••Cl hydrogen bonds,it is a strong chaotropic agent.Guanidine HCl may agglomerate upon storage. It may appear as a free-flowing crystalline powder, a freeflowing powder with solid material dispersed throughout, or a solid. The quality of the product does not appear to be affected and solutions prepared from the free-flowing and lumpy guanidine HCl appear identical

Grade: Ultra Pure
Purity: >99%
Keywords: Guanidium chloride, chaotropic agent
Key Applications: Chaeotropic agent
Product Type: Biochemicals
Biochemical Category: Chaotropic Agents
Density: 1.345 g/cm³ at 20 °C (Lit.)
Melting Point: 180-190 °C
UV/Visible Absorbance: OD260nm (6.0 M aq soln) <0.03
Presentation: White Crystalline Powder
pH: 4-6 (6.0 M aq soln)
Solubility: Soluble in water,Clear, Colorless Solution (6 M - clear, colorless solution).
Storage & Handling: Room Temperature, desiccate

Catalog Number: IC10569680

Supplier: MP Biomedicals

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Description: Glycine is a neutral amino acid and is a primary component in polyacrylamide buffers.

Catalog Number: IB70194

Supplier: IBI Scientific

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Description: Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.

Catalog Number: IC15121091

Supplier: MP Biomedicals

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Description: Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins.

Catalog Number: IC101905.2

Supplier: MP Biomedicals

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Description: [for Protein Research]
CAS Number: 50-01-1
MDL Number: MFCD00013026
Molecular Formula: CH5N3
Molecular Weight: 95.53
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 187

Catalog Number: TCG0197-025G

Supplier: TCI America

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Description: Powerful protein denaturant widely used in purification of proteins and nucleic acids.

Catalog Number: 80058-168

Supplier: MilliporeSigma

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Description: Guanidine Hydrochloride, BiotechGrade is considered a chaotrope and a strong denaturants utilized in physiochemical studies of protein folding. Proteins become randomly coiled at high concentrations of guanidinium chloride. Spectrum offers highly pure reagents suitable for biochemical research and analysis. The critical parameters involved are absence of inhibitors such as traces of heavy metals as well as biochemical function tests for enzymes, coenzymes and enzyme substrates.

Catalog Number: 700007-940

Supplier: Spectrum Chemical Mfg. Corp.

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