You Searched For: Genscript

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.351 (a.k.a. 20H/501Y.V2) is a variant of SARS-CoV-2. It has multiple mutations in the RBD, including K417N, E484K, N501Y. Lineage B.1.1.7 (a.k.a. 20I/501Y.V1) is also a variant of SARS-CoV-2 and has a mutation called N501Y in the RBD.SARS-CoV-2 Spike (E484) Neutralizing Antibody (COV2109) is produced from cell culture <i>in vitro</i> under conditions free from animal-derived components. The product is a humanized neutralizing antibody, recognizing E484 site of wild-type RBD. When E484 is mutated to E484K, the mutant RBD, such as RBD (B.1.351) as seen in Figure 1, can’t be recognized by the product.

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.617 has the double mutations E484Q and L452R in the spike proteins.

Supplier: Genscript

Description: SARS-CoV-2 ADE-causing antibody is a SARS-CoV-2 Spike protein antibody that can exacerbate the COVID-19 disease severity of patients. Antibody-dependent enhancement (ADE) may be involved in the clinical observation of patients with increased severity of symptoms and high levels of SARS-CoV-2 antibodies. It is reported [1] that the same antibodies against the NTD domain of the SARS-CoV-2 spike protein have an ADE effect by increasing the binding of ACE2 to the spike protein.

Catalog Number: (77007-644)

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.Neutralizing antibodies against SARS-CoV-2 can block the interaction between SARS-CoV-2 RBD and ACE2. The blocking ability of SARS-CoV-2 neutralizing antibodies is affected by its quantity. This standard product is intended for the calibration of SARS-CoV-2 neutralizing antibodies in the materials or samples. It can be used in the assessment and development of assays for the detection and quantitation of SARS-CoV-2 neutralizing antibodies. The neutralizing antibody standard binds to multiple neutralizing epitopes in the receptor-binding domain. This product has been verified to calibrate the quantitative assay of SARS-CoV-2 neutralizing antibody with the Surrogate Virus Neutralization Test (sVNT) (GenScript, Cat.No L00847-A), plaque reduction neutralization test (PRNT) and pseudovirus neutralization test (pVNT) (GenScript, Cat.No SC2087). Users can design assays to detect and evaluate the quantitation of SARS-CoV-2 neutralizing antibodies by this product.

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.SARS-CoV-2 Neutralizing Antibody (R323IgM), Human Chimeric is produced from cell culture<i> in vitro</i> under conditions free from animal-derived components.

Catalog Number: (77007-534)

Supplier: Genscript

Description: Sarilumab with the trade name of Kevzara, is a human monoclonal IgG1 antibody. It binds to membrane bound and soluble interleukin 6 (IL-6) receptor forms. It was FDA-approved in for the treatment of Rheumatoid Arthritis (RA) in combination with methotrexate. GenScript anti-sarilumab antibody, pAb, rabbit is produced from sera of a rabbit immunized with Sarilumab.

Catalog Number: (89493-662)

Supplier: Genscript

Description: THE™ Anti-GST Monoclonal antibody (Mouse) recognizes GST localized at the C-terminal, N-terminal and internal region ofGST-tagged fusion proteins.

Catalog Number: (89493-646)

Supplier: Genscript

Description: THE™ DYKDDDDK Tag antibody [HRP], mAb, Mouse recognizes C-terminal, N-terminal and internal tagged fusion proteins.

Catalog Number: (89493-656)

Supplier: Genscript

Description: THE™ GST antibody [HRP], mAb, Mouse recognizes C-terminal, N-terminal and internal tagged GST fusion proteins.

Catalog Number: (89493-666)

Supplier: Genscript

Description: THE™ HA Tag antibody [HRP], mAb, Mouse recognizes C-terminal, N-terminal and internal HA tagged fusion proteins.

Catalog Number: (89493-824)

Supplier: Genscript

Description: Avi Tag Is A Biotin-Acceptor Peptide, Glndifeaqkiewhe. The 15-Residue Peptide Served As A Substrate Mimic For Biotin Ligase (Bira), Which Usually Recognizes The Much Larger Protein Domain. Avi Tag Is A Useful Tool In Analysis Of Avi Fusion Proteins.

Catalog Number: (89495-094)

Supplier: Genscript

Description: THE™ NWSHPQFEK Tag antibody [FITC], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.

Catalog Number: (89495-122)

Supplier: Genscript

Description: THE™ V5 Tag antibody, mAb, Mouse recognizes C-terminal, N-terminal and internal V5 tagged fusion proteins.

Catalog Number: (89494-608)

Supplier: Genscript

Description: GenScript Purified Mouse IgG (Whole Molecule) Control is highly purified from normal mouse serum through Protein A chromatography.GenScript Purified Mouse IgG (Whole Molecule) Control is suitable to be used as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, immunobloting (Dot blot and Western blot), immunoprecipitation, immunodiffusion, and immunoelectrophoresis.It may also be used as antigen or ligand in immunochemical conjugation reaction.

Catalog Number: (89494-374)

Supplier: Genscript

Description: GenScript His-tag antibody [Biotin], pAb, Rabbit specifically reacts with fusion proteins containing His tagged fusion proteins.

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). The B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. WHO has designated B.1.1.529 as a VOC, named Omicron. SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Neutralizing antibodies against SARS-CoV-2 can block the interaction between SARS-CoV-2 RBD and ACE2. The blocking ability of SARS-CoV-2 neutralizing antibodies is affected by the quantity.This standard product is intended for the calibration of SARS-CoV-2 Omicron neutralizing antibodies. It can be used in the assessment and development of assays for the detection and quantitation of SARS-CoV-2 Omicron neutralizing antibodies. The neutralizing antibody standard binds to multiple neutralizing epitopes in the receptor-binding domain.