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Catalog Number: (77007-634)
Supplier: Genscript
Description: Adeno-associated virus (AAV) is a single-stranded DNA virus that commonly infects humans without pathology. Therefore, AAV can be engineered to deliver DNA to target cells as a vector for gene therapy. There are several serotypes including AAV type 1, 2, 5, 6, 8, 9, DJ and rh.1. Among them, AAV2 is the best characterized and most commonly used. Cap gene of AAV gives rise to three capsid proteins, VP1, VP2 and VP3, with molecular weight of 87, 72 and 62 kDa respectively. These capsid proteins assemble into a near-spherical protein shell of 60 subunits for AAV.


Catalog Number: (77007-482)
Supplier: Genscript
Description: CD8 (cluster of differentiation 8) is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 antigen is existed as a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. CD8+ cytotoxic T cells are crucial for the killing of virus-infected cells and tumor cells.


Catalog Number: (77007-558)
Supplier: Genscript
Description: Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-alpha, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-alpha blocker to disrupt the interaction of TNF-alpha with its receptors. GenScript Anti-Infliximab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Infliximab.


Catalog Number: (77007-540)
Supplier: Genscript
Description: Adeno-associated virus type 8 (AAV8) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV8 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa respectively.


Supplier: Genscript
Description: Accessories for eBlot® L1 Fast Wet Transfer System for Mini Gels

Catalog Number: (77007-476)
Supplier: Genscript
Description: Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumours growth and metastasis by weakening tumour angiogenesis.


Catalog Number: (77007-624)
Supplier: Genscript
Description: Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5 or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.Anti-Eculizumab Antibody (13F5), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with eculizumab.


Catalog Number: (77007-504)
Supplier: Genscript
Description: A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.


Catalog Number: (77007-524)
Supplier: Genscript
Description: Secukinumab with brand name Cosentyx, is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is marketed by novartis for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells. IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor. Anti-Secukinumab antibody (23E11), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Secukinumab.


Catalog Number: (89233-330)
Supplier: Genscript
Description: The ToxinEraser™ endotoxin removal resin utilizes immobilized polymixin B to bind and remove pyrogens from solution.


Catalog Number: (89494-988)
Supplier: Genscript
Description: GenScript Streptavidin Antibody is specific to streptavidin.


Catalog Number: (89493-642)
Supplier: Genscript
Description: THE™ c-Myc Tag antibody, mAb, Mouse recognizes C-terminal, N-terminal and internal c-Myc tagged fusion proteins expressed in prokaryotic or eukaryotic cells. It also recognizes c-Myc protein in human cancers or cell lines such as Hela cell lysates.


Catalog Number: (89493-650)
Supplier: Genscript
Description: THE™ DYKDDDDK Tag antibody, mAb, Mouse recognizes DYKDDDDK; tags localized at the C-terminal, N-terminal and internal region of DYKDDDDK
tagged fusion proteins.


Catalog Number: (76198-912)
Supplier: Genscript
Description: GenScript MonoRab™ DYKDDDDK tag antibody, mAb, rabbit specifically recognizes DYKDDDDK tags placed at C-terminal, N-terminal and internal regions of DYKDDDDK fusion proteins.


Catalog Number: (76197-362)
Supplier: Genscript
Description: The product is specific for Rituximab. This antibody serves as an excellent positive control for Rituximab immunogenicity (ADA) assays.


Catalog Number: (76510-444)
Supplier: Genscript
Description: eBlot™ L1 wet protein transfer system is a fast western blotting protein transfer system that combines the high reproducibility and efficiency of the traditional wet protein transfer with the speed and convenience of semi-dry protein transfer. It allows efficient western blot transfer of small, medium, and large molecular weight proteins.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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