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Product Image-77751-670

Human Recombinant GDF-5 (from E. coli)

Description: Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues.
Catalog Number: 77751-670
Supplier: VWR International

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Product Image-77752-372

Mouse Recombinant MIP-1 B (from E. coli)

Description: Macrophage inflammatory protein-1 beta (MIP-1 β), also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1 β signals through the chemokine receptor CCR5 to chemoattract immune cells.
Catalog Number: 77752-372
Supplier: VWR International

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Product Image-77750-692

Human Recombinant GDF-15 (from E. coli)

Description: Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury.
Catalog Number: 77750-692
Supplier: VWR International

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Product Image-77752-850

Rat Recombinant EGF (from E. coli)

Description: Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. EGF contains three intramolecular disulfide bonds and binds in high affinity to the epidermal growth factor receptor (EGFR).
Catalog Number: 77752-850
Supplier: VWR International

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Product Image-77751-932

Mouse Recombinant Rank Ligand (from E. coli)

Description: Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.
Catalog Number: 77751-932
Supplier: VWR International

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Product Image-77753-104

Rat Recombinant SHH (from E. coli)

Description: Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.
Catalog Number: 77753-104
Supplier: VWR International

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Product Image-77750-074

Human Recombinant SCF (from E. coli)

Description: Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.
Catalog Number: 77750-074
Supplier: VWR International

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Product Image-77751-886

Mouse Recombinant IL-3 (from E. coli)

Description: Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells.  IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells.  IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.  
Catalog Number: 77751-886
Supplier: VWR International

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Product Image-77751-714

Human Recombinant IL-3 (from E. coli)

Description: Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.
Catalog Number: 77751-714
Supplier: VWR International

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Product Image-77751-732

Human Recombinant PSP (from E. coli cells)

Description: Persephin is a neurotrophic factor of the glial cell line-derived neurotrophic factor (GDNF) family. Persephin promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. Persephin is a ligand for the RET receptor tyrosine kinase.
Catalog Number: 77751-732
Supplier: VWR International

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Product Image-77752-936

Rat Recombinant TNF-A (from E. coli)

Description: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2.
Catalog Number: 77752-936
Supplier: VWR International

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Product Image-77751-876

Mouse Recombinant IL-3 (from E. coli)

Description: Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells.  IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells.  IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.  
Catalog Number: 77751-876
Supplier: VWR International

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Product Image-77750-066

Human Recombinant SCF (from E. coli)

Description: Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a critical role in the maintenance, survival, and differentiation of hematopoietic stem cells. While human SCF shows no activity on murine cells, murine and rat SCF are active on human cells.
Catalog Number: 77750-066
Supplier: VWR International

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Product Image-77751-392

Human Recombinant TNFR-1 (from E. coli)

Description: Tumor necrosis factor receptor type 1 (TNFR-1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNF-α). TNFR-1 activates NF-κB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.
Catalog Number: 77751-392
Supplier: VWR International

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Product Image-77750-912

Human Recombinant Rank Ligand (from E. coli)

Description: Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.
Catalog Number: 77750-912
Supplier: VWR International

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Product Image-77753-566

Human Recombinant SDF-1 B/CXCL12 (from E. coli)

Description: <p>Stromal cell-derived factor-1 beta (SDF-1 β), also called CXCL12b, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1 β signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes.</p>
Catalog Number: 77753-566
Supplier: VWR International

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