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Image Unavailable-75924-846

Anti-ESR1 Mouse Monoclonal Antibody (CF568) [clone: AER314]

Supplier: Biotium
Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Image Unavailable-10234-076

Anti-ESR2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10234-076)
Supplier: Bioss
Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Image Unavailable-10234-080

Anti-ESR2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10234-080)
Supplier: Bioss
Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Image Unavailable-10232-616

Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10232-616)
Supplier: Bioss
Description: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Image Unavailable-10232-614

Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10232-614)
Supplier: Bioss
Description: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Image Unavailable-10232-612

Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10232-612)
Supplier: Bioss
Description: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Product Image-10232-596

Anti-Estrogen Receptor alpha + beta Rabbit Polyclonal Antibody

Catalog Number: (10232-596)
Supplier: Bioss
Description: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.
Product Image-JTM376-7

Iron(III) citrate monohydrate, J.T.Baker®

Catalog Number: (JTM376-7)
Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: Ferric Citrate, n-Hydrate, BAKER

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Product Image-97061-732

Diammonium hydrogen citrate, high purity

Catalog Number: (97061-732)
Supplier: VWR
Description: Diammonium hydrogen citrate, high purity

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Product Image-99991-164

Anti-ESR Rabbit Monoclonal Antibody [clone: SP1]

Supplier: Diagnostic Biosystems
Description: This antibody recognizes a protein of 67kDa, which is identified as estrogen receptor (ER). ER content of breast cancer tissue is an important parameter in the prediction of prognosis and response to endocrine therapy. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Image Unavailable-75924-858

Anti-ESR1 Mouse Monoclonal Antibody (CF568) [clone: ER506]

Supplier: Biotium
Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Image Unavailable-75925-998

Anti-ESR1 Mouse Monoclonal Antibody (CF405S) [clone: ESR1/420]

Supplier: Biotium
Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa300-550. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Image-MK7773-04

tri-Sodium citrate dihydrate 99.0-100.5% (by anhydrous basis), crystals, GenAR® USP, Multi-Compendial, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: Crystals. For biotechnology. GMP manufactured.

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Image Unavailable-10231-700

Anti-ESR2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10231-700)
Supplier: Bioss
Description: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Product Image-JT3647-1

tri-Sodium citrate dihydrate ≥99% (by anhydrous basis), granular BP, Ph. Eur., JP, USP, Multi-Compendial, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: Granular. GMP manufactured.

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Product Image-89230-082

Ammonium bismuth citrate ≥99%, Reagent Grade

Catalog Number: (89230-082)
Supplier: VWR
Description: Ammonium bismuth citrate ≥99%, Reagent Grade

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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