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Ultrafiltration Membrane Disc Filters

Supplier: Cytiva

Description: Replacement membranes for conventional, nondisposable stirred cell systems.

NAB Nanosep® Centrifugal Devices for RNA and DNA Extraction, Cytiva (Formerly Pall Lab)

Supplier: Cytiva

Description: NAB Nanosep® is a low cost alternative to expensive kits that yields quantity and quality of nucleic acid suitable for downstream applications, such as PCR, sequencing, and RE digestion. NAB nanoseps offer various protocols that help the end user save money without sacrificing results.

Anti-KIRREL3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10264-944)

Supplier: Bioss

Description: NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).

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Anti-KIRREL3 Rabbit Polyclonal Antibody

Catalog Number: (10264-932)

Supplier: Bioss

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Anti-KIRREL3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10264-948)

Supplier: Bioss

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Human Hepcidin-25 Trifluoroacetate

Supplier: Bachem Americas

Description: Hepcidin-25 (hepatic bactericidal protein), also referred to as LEAP-1 (liver-expressed antimicrobial peptide) has been independently discovered by two groups in human blood ultrafiltrate and urine. The peptide which is predominantly expressed in the liver, belongs to a new vertebrate family of small antimicrobial peptides that contain 8 cysteine residues and show significant antibacterial and antifungal activity. Further investigations revealed that hepicidin is the principal iron-regulatory hormone in humans. It acts by binding to the iron exporter ferroportin, inducing its internalization and degradation, thereby blocking cellular iron efflux. Nemeth et al. demonstrated that the N-terminal part of the peptide hormone is essential for its activity.
Synonym: Hepc25 (human), LEAP-1 (human), Liver-Expressed Antimicrobial Peptide (human), PLTR (human), Putative Liver Tumor Regressor (human)
Sequence: H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH
Salt: Trifluoroacetate
Bonds: (Disulfide bonds between Cys7 and Cys23/Cys10 and Cys13/Cys11 and Cys19/Cys14 and Cys22)