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Supplier: Spectrum Chemicals
Description: L-Selenomethionine, also known as MSE, is an amino acid containing selenium and readily oxidized. Its ability to deplete reactive oxygen species causes its antioxidant activity.

Catalog Number: (IC091676649)
Supplier: MP Biomedicals
Description: MP Biomedicals offers a 1000X sterile filtered solution for use with serum-free media.


Catalog Number: (10395-208)
Supplier: Bioss
Description: Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.


Catalog Number: (10297-720)
Supplier: Bioss
Description: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1–8). GPx-7 (glutathione peroxidase 7), also known as GPX6, CL683 or NPGPx, is a 187 amino acid secreted protein belonging to the glutathione peroxidase family. GPx-7 catalyzes the reaction of glutathione into glutathione disulfide and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.


Catalog Number: (76077-978)
Supplier: Bioss
Description: HIF1AN (Hypoxia inducible factor 1 alpha inhibitor) is a corepressor that interacts with hypoxia inducible factor 1 (HIF1) alpha and the von Hippel Lindau tumor suppressor protein to mediate repression of HIF1 transcriptional activity.


Catalog Number: (76077-980)
Supplier: Bioss
Description: HIF1AN (Hypoxia inducible factor 1 alpha inhibitor) is a corepressor that interacts with hypoxia inducible factor 1 (HIF1) alpha and the von Hippel Lindau tumor suppressor protein to mediate repression of HIF1 transcriptional activity.


Catalog Number: (75793-558)
Supplier: Prosci
Description: Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma.


Catalog Number: (76072-500)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100


Catalog Number: (103277-768)
Supplier: Novus Biologicals
Description: The Peroxiredoxin 6 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Peroxiredoxin 6. This antibody reacts with human. The Peroxiredoxin 6 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.


Supplier: Adipogen
Description: The 2,3-diaminonaphthalene (DAN) assay is routinely used in the determination of nitrite/nitrate levels in biological fluids and cellular extracts as one indicator of nitric oxide activity. The assay, as reported by Misko, uses the reaction of DAN with NO2- under acidic conditions to form a detectable fluorescent naphthotriazole. The reaction proceeds at acidic pH at room temperature. Fluorescence is monitored following the addition of NaOH, which raises pH, resulting in lower background and increased sensitivity (Ex/Em: ~365/415nm). However, detection at 450nm is recommended to avoid fluorescent blanks and increase sensitivity. The fluorescent background of DAN is low for maximum sensitivity. Detection limits of NO achieved by this method are in the high-pM range. 2,3-Diaminonaphtaline (DAN) is used as a derivatisation-reagent for the determination of selenium at low detection limits. The 4,5-benzopiaselenol-complex can be quantified by photometry or GC.

Supplier: Invitria
Description: InVitria’s ITS Animal-Free™ is formulated to reduce serum from cell culture media.

SDS

Supplier: Invitria
Description: InVitria’s ITSE+A Animal-Free™ is formulated for optimal enhancement of serum free media.

SDS

Catalog Number: (95057-259)
Supplier: Greiner Bio-One
Description: VACUETTE® trace element tubes are designed to test trace elements such as aluminum, lead, cadmium, chrome, iron, fluoride, cobalt, copper, lithium, manganese, molybdenum, mercury, selenium, or thalium.

Supplier: Spectrum Chemicals
Description: Sodium Selenite, 99.8+ Percent, Powder is the most common selenium compound that is soluble in water. It is a solid that has no color and is a salt. Its most common use is in the glass industry but it is also used as a food supplement due to its nature as an essential element
Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: The quality of BAKER ANALYZED™ ACS Reagents meets or exceeds the requirements set forth by the American Chemical Society (ACS). These acids are tested for common trace metals.
Catalog Number: (BDH7921-1)
Supplier: VWR International
Description: Suitable as a calibration standard.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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