You Searched For: Poloxamer+181+(Pluronic®+L-61,+Synperonic®+L61)


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Catalog Number: (76078-564)
Supplier: Bioss
Description: CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.


Catalog Number: (76107-518)
Supplier: Bioss
Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF180 (ring finger protein 180), also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger. Expressed as three alternatively spliced isoforms, RNF180 is well conserved among vertebrates. RNF180 is expressed in brain, kidney, testis and uterus and localizes to the endoplasmic reticulum. RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway. RNF180 is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.


Catalog Number: (10424-048)
Supplier: Bioss
Description: CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.


Supplier: FUJIFILM IRVINE SCIENTIFIC, INC
Description: Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.

Catalog Number: (10263-664)
Supplier: Bioss
Description: Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.


Catalog Number: (10263-666)
Supplier: Bioss
Description: Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.


Catalog Number: (103345-874)
Supplier: Novus Biologicals
Description: The RCSD 1 Antibody (3F6) from Novus Biologicals is a mouse monoclonal antibody to RCSD 1. This antibody reacts with human. The RCSD 1 Antibody (3F6) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (76010-912)
Supplier: Prosci
Description: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex (By similarity).


Catalog Number: (103334-384)
Supplier: Novus Biologicals
Description: The ZNF232 Antibody (1F8) from Novus Biologicals is a mouse monoclonal antibody to ZNF232. This antibody reacts with human. The ZNF232 Antibody (1F8) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry-Paraffin.


Catalog Number: (76009-154)
Supplier: Prosci
Description: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).


Catalog Number: (103341-758)
Supplier: Novus Biologicals
Description: The PITPNB Antibody (3D3) from Novus Biologicals is a mouse monoclonal antibody to PITPNB. This antibody reacts with human. The PITPNB Antibody (3D3) has been validated for the following applications: Western Blot, ELISA.


Catalog Number: (103326-940)
Supplier: Novus Biologicals
Description: The GALK1 Antibody (2E9.) from Novus Biologicals is a mouse monoclonal antibody to GALK1. This antibody reacts with human. The GALK1 Antibody (2E9.) has been validated for the following applications: Western Blot, ELISA.


Catalog Number: (103346-298)
Supplier: Novus Biologicals
Description: The NIRF Antibody (3A11) from Novus Biologicals is a mouse monoclonal antibody to NIRF. This antibody reacts with human. The NIRF Antibody (3A11) has been validated for the following applications: Western Blot, ELISA, Immunocytochemistry / Immunofluorescence.


Catalog Number: (103275-164)
Supplier: Novus Biologicals
Description: The ZNHIT6 Antibody from Novus Biologicals is a rabbit polyclonal antibody to ZNHIT6. This antibody reacts with human. The ZNHIT6 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.


Catalog Number: (103341-548)
Supplier: Novus Biologicals
Description: The Dimethylarginine Dimethylaminohydrolase 1 / DDAH1 Antibody (3F7) from Novus Biologicals is a mouse monoclonal antibody to Dimethylarginine Dimethylaminohydrolase 1 / DDAH1. This antibody reacts with human. The Dimethylarginine Dimethylaminohydrolase 1 / DDAH1 Antibody (3F7) has been validated for the following applications: Western Blot, ELISA.


Catalog Number: (103345-310)
Supplier: Novus Biologicals
Description: The CYorf15A Antibody (2F5) from Novus Biologicals is a mouse monoclonal antibody to CYorf15A. This antibody reacts with human. The CYorf15A Antibody (2F5) has been validated for the following applications: Western Blot, ELISA, Adhesion Blockade.


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