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Product Image-76360-416

Polytron® Generator, PT-DA/2MEC, Kinematica

Supplier: Kinematica
Description: M-design rotor with knives for pre-cutting. Outside blades pre-crush samples that are larger than the rotors diameter. Subsequently, they can be dispersed inside the generator. Dispersing generators are made from high-alloy stainless steel 316L, electropolished, Ra≤1.6 μm as standard.

Small Business Enterprise

Product Image-95029-770

Anti-MLH1 Mouse Monoclonal Antibody [clone: G168-15]

Supplier: Diagnostic Biosystems
Description: The G168-15 antibody recognizes human and mouse MLH1 (80-85kDa). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Product Image-BDH7781-2

Polysorbate 80 solution analytical reagent, VWR Chemicals BDH®

Catalog Number: (BDH7781-2)
Supplier: VWR International
Description: Polysorbate 80 solution analytical reagent, VWR Chemicals BDH®

SDS Certificates


Image Unavailable-76634-406

Anti-MLH-1 Mouse Monoclonal Antibody [clone: G168-15]

Catalog Number: (76634-406)
Supplier: Diagnostic Biosystems
Description: The G168-15 antibody recognizes human and mouse MLH1 (80 to 85 kDa). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.
Product Image-75834-408

Nalgene® Certified Platinum Clean HDPE Bottles and Carboys, Sterile, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: Thermo Scientific Nalgene® certified platinum clean HDPE bottles and carboys help reduce the potential for carry-over contamination.

Certificates

Product Image-76360-420

Polytron® Generator, PT-DA/2EC-E192, Kinematica

Supplier: Kinematica
Description: Standard dispersing generators come with the EC (EasyClean) design and rotor/stator geometries with two, four or six teeth rows. This is all you need for popular applications in the preparation of samples, formulation development and small-scale production. Dispersing generators are made from high-alloy stainless steel 316L, electropolished, Ra≤1.6 μm as standard.

Small Business Enterprise

Product Image-76360-428

Polytron® Generator, PT-DA/BEC (BIOTRONA), Kinematica

Supplier: Kinematica
Description: BIOTRONA® design high turbulence mixing. High-turbulence mixing head with low shear forces and energy inputs. Time saving with improved results compared to stirrers and dissolvers of up to 90%. Dispersing generators are made from high-alloy stainless steel 316L, electropolished, Ra≤1.6 μm as standard.

Small Business Enterprise

Image Unavailable-76633-894

Anti-MLH-1 Mouse Monoclonal Antibody [clone: G168-15]

Supplier: Diagnostic Biosystems
Description: The G168-15 antibody recognizes human and mouse MLH1 (80 to 85 kDa). The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSH-2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Image Unavailable-75915-448

Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody [clone: C66/1030]

Catalog Number: (75915-448)
Supplier: Biotium
Description: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Image Unavailable-75917-314

Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody [clone: C66/1009]

Supplier: Biotium
Description: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Product Image-89051-238

Adapter, Adjustable Electrode, with Joint, Ace-Thred, Ace Glass Incorporated

Supplier: Ace Glass
Description: This Ace-Thred adapter is used with platinum or other wire electrodes that normally would be step sealed to glass.

Small Business Enterprise Product available on GSA Advantage®

Image Unavailable-10305-196

Anti-Claudin 23 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10305-196)
Supplier: Bioss
Description: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80% sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.
Image Unavailable-75916-766

Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody (Biotin) [clone: C66/1030]

Supplier: Biotium
Description: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Image Unavailable-75916-756

Anti-CEACAM1 & CEACAM5 Mouse Monoclonal Antibody [clone: C66/1030]

Supplier: Biotium
Description: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA positive) from pleural mesotheliomas (rarely or weakly CEA positive) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Image Unavailable-AA11828-22

Tungsten trioxide ≥99.8% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: In manufacture of tungsten and tungstates, and in alloys, in fire-proofing fabrics, and as a ceramic pigment

SDS Certificates

Image Unavailable-10305-202

Anti-Claudin 23 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10305-202)
Supplier: Bioss
Description: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80% sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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