You Searched For: PBDB-T-2F+(PCE14)

Supplier: Thermo Scientific Chemicals

Description: PBDB-T-2F (PCE14), Poly[[4,8-bis[5-(2-ethylhexyl)-4-fluoro-2-thienyl]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c']dithiophene-1,3-diyl]-2,5-thiophenediyl], Formula: (C68H76F2O2S8)n, Synonyms: PCE135, Storage: Ambient, Size: 100mg

Supplier: Thermo Scientific Chemicals

Description: PBDB-T-2Cl, Poly[[4, 8-bis[4-chloro-5-(2-ethylhexyl)-2-thienyl]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c]dithiophene-1,3-diyl]-2,5-thiophenediyl], Synonyms: PCE 139, Formula: (C68H76Cl2O2S8)n, Storage: Ambient, Size: 500mg

Supplier: Thermo Scientific Chemicals

Description: PBDB-T (PCE12), Poly[(2,6-(4,8-bis(5-(2-ethylhexyl)thiophen-2-yl)-benzo[1,2-b:4,5-b]dithiophene))-alt-(5,5-(1,3-di-2-thienyl-5,7-bis(2-ethylhexyl)benzo[1,2-c:4,5-c]dithiophene-4,8-dione)], Formula: (C68H78O2S8)n, Storage and Sensitivity: Ambient temperatures, Size: 500mg

Catalog Number: (82021-174)

Supplier: VWR International

Description: Organic liquid thermometer features a U-shaped tube mounted on a plastic casing with metal floats at the top of each column.

Supplier: Adipogen

Description: For application to living cells, the diacetyl derivative of ZnAF-2F, ZnAF-2F DA, was synthesized. ZnAF-2F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-2F, which is retained in the cells. Using ZnAF-2F DA we could measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices. Spectral data: lambdaex 492nm; lambdaem 515nm in PBS.

Supplier: Adipogen

Description: ZnAF-1F and ZnAF-2F do not fluoresce in the presence of other biologically important cations such as Ca2+ and Mg2+, and are insensitive to change of pH. The complexes with Zn2+ of previously developed ZnAFs, ZnAF-1, and ZnAF-2 decrease in fluorescence intensity below pH 7.0 owing to protonation of the phenolic hydroxyl group of fluorescein, whose pKa value is 6.2. On the other hand, the Zn2+ complexes of ZnAF-1F and ZnAF-2F emit stable fluorescence around neutral and slightly acidic conditions because the pKa values are shifted to 4.9 by substitution of electron-withdrawing fluorine at the ortho position of the phenolic hydroxyl group. Spectral data: lambdaex 492nm; lambdaem 517nm in PBS.

Catalog Number: (102902-018)

Supplier: Affymetrix, Inc.

Description: The monoclonal antibody 26-2F recognizes human angiogenin. Angiogenin is a secreted ribonuclease (RNASE)-family member and is important for the formation of new blood vessels as well as the stimulation of cell proliferation and survival. Cellular stress signals direct angiogenin to stress granules where angiogenin functions by hydrolyzing cellular tRNA resulting in modulation of protein translation and promotion of cell survival. Cytoplasmic angiogenin can bind to actin, forming complexes that activate protease cascades which can degrade laminin and fibronectin allowing endothelial cells to penetrate the basement membrane and migrate. In cancer cells, growth signals direct angiogenin translocation to the nucleus where binding of DNA promotor regions stimulates rRNA transcription resulting in a downstream increase in protein synthesis driving cell growth and survival. Angiogenin is upregulated in multiple cancers including breast, prostate, cervical, colorectal, lymphoma, and melanoma. During development and in adulthood, angiogenin is highly expressed in the spinal cord and contributes to motor neuron survival. Angiogenin is important for neuronal survival and is depleted in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease. This 26-2F antibody is reported to have both in vivo and in vitro neutralizing activity to angiogenin. Applications Reported: This 26-2F antibody has been reported for use in cytokine neutralization, immunoprecipitation, immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, ELISA, and immunocytochemistry. Applications Tested: This 26-2F antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low or high pH antigen retrieval and can be used at less than or equal to 20 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

Catalog Number: (101649-064)

Supplier: MilliporeSigma

Description: Anti-GSK3B Mouse Monoclonal Antibody [clone: 5G-2F]

Catalog Number: (100244-038)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 17-3-3 reacts with the I-Ek class II alloantigen on cells from mice of the H-2r haplotype. Reactivity with H-2d and H-2p haplotypes has not been observed. Cells from mice of the H-2b, H-2f, H-2g, H-2q, and H-2s haplotypes do not express I-E antigen.

Catalog Number: (76208-240)

Supplier: HexArmor

Description: Safety eyewear should never be treated as one size fits all. Simply wearing any generic pair of safety eyewear isn’t enough to protect the eyes.100% UV protection, metal-free

Catalog Number: (77439-196)

Supplier: Bioss

Description: The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008].

New Product

Catalog Number: (100244-032)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 14-4-4S reacts with the I-Ek class II alloantigen on cells from mice of the H-2d, H-2p, and H-2r haplotypes. Cells from mice of the H-2b, H-2f, H-2q, and H-2s haplotypes do not express I-E antigen. The antibody has been reported to cross-react with the rat MHC class II alloantigen RT1D.

Catalog Number: (103470-454)

Supplier: Affymetrix, Inc.

Description: MA1-90088 detects TCP1 beta from mouse samples. MA1-90088 has been successfully used in Western blot applications. The MA1-90088 immunogen is: TCP1 beta peptide conjugated to purified tuberculin protein derivative (PPD) (Mouse).

Catalog Number: (102902-016)

Supplier: Affymetrix, Inc.

Description: The monoclonal antibody 26-2F recognizes human angiogenin. Angiogenin is a secreted ribonuclease (RNASE)-family member and is important for the formation of new blood vessels as well as the stimulation of cell proliferation and survival. Cellular stress signals direct angiogenin to stress granules where angiogenin functions by hydrolyzing cellular tRNA resulting in modulation of protein translation and promotion of cell survival. Cytoplasmic angiogenin can bind to actin, forming complexes that activate protease cascades which can degrade laminin and fibronectin allowing endothelial cells to penetrate the basement membrane and migrate. In cancer cells, growth signals direct angiogenin translocation to the nucleus where binding of DNA promotor regions stimulates rRNA transcription resulting in a downstream increase in protein synthesis driving cell growth and survival. Angiogenin is upregulated in multiple cancers including breast, prostate, cervical, colorectal, lymphoma, and melanoma. During development and in adulthood, angiogenin is highly expressed in the spinal cord and contributes to motor neuron survival. Angiogenin is important for neuronal survival and is depleted in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease. This 26-2F antibody is reported to have both in vivo and in vitro neutralizing activity to angiogenin. Applications Reported: This 26-2F antibody has been reported for use in cytokine neutralization, immunoprecipitation, immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, ELISA, and immunocytochemistry. Applications Tested: This 26-2F antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low or high pH antigen retrieval and can be used at less than or equal to 20 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

Catalog Number: (100244-130)

Supplier: Southern Biotechnology

Description: The monoclonal antibody 15-5-5 reacts with the H-2Dk class I alloantigen. It cross-reacts with H-2Kd and with cells from mice with the H-2f haplotype. The antibody does not react with other (e.g., a, b, p, q, r, s) haplotypes.

Catalog Number: (110307-BL)

Supplier: Biolegend

Description: PE anti-mouse H-2Dk [15-5-5]; Isotype: Mouse (C3H.SW) IgG2a, κ; Reactivity: Mouse k haplotype, Cross-reacts with H-2Kd and H-2f haplotypes. Does not cross react with other haplotypes (e.g., a, b, p, q, r, s).; Apps: FC; Size: 50 μg