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Wogonin ≥98% (by HPLC)

Supplier: Adipogen
Description: Anti-inflammatory. Increases nitric oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. Telomerase activity inhibitor. CDK9 inhibitor. PI3K-AKT pathway modulator. Autophagy inducer.

Product Image-89150-848

PTIO (=2-phenyl-4,4,5,5-tetramethylimidazoline-3-oxide-1-oxyl) ≥98% (by non aqueous titration)

Catalog Number: (89150-848)
Supplier: Enzo Life Sciences
Description: Stable nitric oxide (NO) radical scavenger.
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Bovine;Human;Mouse;Rat Apelin-12

Supplier: Bachem Americas
Description: Apelin-12, RPRLSHKGPMPF, is an endogenous ligand of the human orphan receptor APJ and has been shown to reduce arterial blood pressure without producing a change in the heart rate in anesthetized rats. Its vasoactive effect might be exerted by activation of endothelial nitric oxide synthase.

Image Unavailable-80051-406

Diphenyleneiodonium chloride, Calbiochem®

Catalog Number: (80051-406)
Supplier: MilliporeSigma
Description: Irreversible endothelial nitric oxide synthase inhibitor. Inhibits iNOS in macrophages (IC50=50nM). CAS: 4673-26-1. Purity: >97% by TLC. Soluble in DMSO. FW: 314.6. 10mg white solid.

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Product Image-77664-474

Nitric Oxide Macro Sensor

Catalog Number: (77664-474)
Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: The ISO-NOP is a popular, robust and high performance sensor encased within a 2 mm diameter disposable stainless steel protective sleeve. The tip of the sleeve is covered with a NO-selective membrane. Replacement membrane sleeves can be purchased separately and require an internal electrolyte.

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Image Unavailable-76001-960

Rat Recombinant nNOS

Catalog Number: (76001-960)
Supplier: Enzo Life Sciences
Description: Produced in E. coli. Untagged rat nNOS.
Image Unavailable-77439-146

Anti-iNos/Nos-2, Rabbit Polyclonal Antibody

Catalog Number: (77439-146)
Supplier: Bioss
Description: Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. Nitric oxide synthase is expressed in liver, macrophages, hepatocytes, synoviocytes, stimulated glial cells and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOS2).
Image Unavailable-77439-754

Anti-iNOS Rabbit Polyclonal Antibody

Catalog Number: (77439-754)
Supplier: Bioss
Description: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Product Image-89146-982

PKCζ PseudoSubstrate

Catalog Number: (89146-982)
Supplier: Enzo Life Sciences
Description: Selective cell permeable inhibitor of PKCζ. Activates eNOS (NOS III) through Akt phosphorylation and can be considered as a nitric oxide production activator in endothelial cells.
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DAR-4 ≥98% (by NMR)

Supplier: Adipogen
Description: Photo-stable fluorescent probe for the detection of nitric oxide (NO).

Image Unavailable-10336-438

Anti-NOS2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10336-438)
Supplier: Bioss
Description: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Product Image-MSPP-PAA837MU1

Anti-NOS2 Rabbit Polyclonal Antibody

Catalog Number: (MSPP-PAA837MU1)
Supplier: CLOUD-CLONE CORP MS
Description: Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2), derived from recombinant NOS2 (Asp43~Thr213), is reactive with Mouse/Rat.

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1(H)-Naphthotriazol ≥98% (by HPLC)

Supplier: Adipogen
Description: Fluorescent probe. Used for the detection of nitrite, nitric oxide release and S-nitrosothiols (RSNOs). Activatable DNA cleaving agent.

Image Unavailable-89298-176

Anti-CAPON / NOS1AP (nitric oxide Synthase 1 (neuronal) adaptor Protein) Goat Polyclonal Antibody

Catalog Number: (89298-176)
Supplier: Genetex
Description: Goat polyclonal antibody to CAPON / NOS1AP
Image Unavailable-10814-278

Ebselen, powder

Catalog Number: (10814-278)
Supplier: Thermo Scientific Chemicals
Description: Seleno-organic compound that inhibits nitric oxide-induced apoptosis. Potent antioxidant. Protects calcium influx blockage

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Image Unavailable-80057-038

S-Methyl-L-thiocitrulline dihydrochloride, Calbiochem®

Catalog Number: (80057-038)
Supplier: MilliporeSigma
Description: Exhibits about 17-fold greater selectivity for rat neuronal nitric oxide synthase (IC50=0.3nM) compared to the endothelial enzyme (IC50=5.4uM). Purity: >=90% by TLC. Soluble in water. FW: 278.2. 10mg white solid.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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