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You Searched For: NF-\\u03BAB+Activation+Inhibitor+III


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Product Image-76293-016

NF-κB Activation Inhibitor III ≥99%

Supplier: Cayman Chemical Company
Description: NF-KB Activation Inhibitor III, Purity >/=99%, CAS 380623-76-7, MF: C10H5ClN4O5S, MW: 328.7, Synonyms: SM-7368, 3-chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide, Formulation: A crystalline solid, Storage: -20C, Size: 5mg

Image Unavailable-77439-660

Anti-IKK Gamma Rabbit Polyclonal Antibody

Catalog Number: (77439-660)
Supplier: Bioss
Description: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3.

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Product Image-10068-698

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10068-698)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-κ-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-κ-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-κ-B-regulated promoters during inflammatory responses triggered by cytokines.
Image Unavailable-102516-104

CHS-828 ≥98%

Supplier: Adipogen
Description: Antitumor compound. Programmed cell death inducer. Cytotoxic. Antiproliferative. p53 activator. IkappaB kinase inhibitor. NF-kappaB inhibitor. Nampt/visfatin inhibitor.

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Product Image-10813-826

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10813-826)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3.
Image Unavailable-102979-958

Anti-Nuclear Factor NF-kappaB Essential Modulator;NEMO;IKKG;FIP-3 Rabbit Polyclonal Antibody

Catalog Number: (102979-958)
Supplier: Adipogen
Description: IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response.
Product Image-76293-022

NF-κB Inhibitor (SN50)

Supplier: Cayman Chemical Company
Description: A synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

Image Unavailable-82603-174

MK-2 Inhibitor III hydrate ≥97% (by HPLC), Calbiochem®, Sigma-Aldrich®

Catalog Number: (82603-174)
Supplier: MilliporeSigma
Description: The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

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Product Image-10068-838

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10068-838)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-κ-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-κ-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-κ-B-regulated promoters during inflammatory responses triggered by cytokines.
Image Unavailable-103008-418

NF-kB Inhibitor

Catalog Number: (103008-418)
Supplier: Anaspec Inc
Description: SN50 is a NF-κB cell-permeable inhibitory peptide. it consists of the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor (K-FGF) attached to a NF-kB p50 nuclear localization sequence (NLS). SN50 inhibits translocation of the NF-kB active complex into the nucleus.
Sequence:AAVALLPAVLLALLAPVQRKRQKLMP
MW:2781.5 Da
% peak area by HPLC:95
Storage condition:-20° C
Product Image-89146-810

Protease Inhibitor I aldehyde

Supplier: Enzo Life Sciences
Description: Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

Image Unavailable-89149-082

Panepoxydone (from Lentinus crinitus) ≥95% (by HPLC, MS)

Catalog Number: (89149-082)
Supplier: Enzo Life Sciences
Description: Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
Image Unavailable-76293-012

JSH-23 ≥98%

Supplier: Cayman Chemical Company
Description: JSH-23, Purity >/=98%, CAS 749886-87-1, MF: C16H20N2, MW: 240.3, Synonyms: NF-KB Activation Inhibitor II, 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine, Formulation: A crystalline solid, Storage: -20C, Size: 5mg

Image Unavailable-77439-122

Anti-IKK beta Rabbit Polyclonal Antibody

Catalog Number: (77439-122)
Supplier: Bioss
Description: The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. (provided by RefSeq, Sep 2011).

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Product Image-10069-028

Anti-IKBKB Rabbit Polyclonal Antibody

Catalog Number: (10069-028)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Image Unavailable-102513-796

(R)-Semivioxanthin ≥98% (by HPLC)

Supplier: Adipogen
Description: Mycotoxin. Antibacterial (Gram-positive) and antifungal. Immunoregulator by degradation of IkappaB (Inhibitor of NF-kappaB) and regulation of the TNF-alpha (tumor necrosis factor-alpha) and MAPK (mitogen-activated protein kinase) signaling pathways.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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